Registered Nurse Salary in Mount Pleasant, SC: $87,258 (2026)
Quick Answer:A full-time registered nurse in Mount Pleasant, SC earns a median $87,258/year (≈ $41.96/hour) in nominal terms for 2026 — projected from BLS OEWS 2025 (SOC 29-1141). Once you factor in Mount Pleasant's price level (8% below national, BEA RPP 91.5), that paycheck buys what $95,364 would nationally. Nominal pay sits 1.5% above the South Carolina state average.
Based on BLS state-level estimates · View source

In Mount Pleasant, South Carolina, registered nurses can expect a median annual salary of $87,258 in 2026, which reflects a significant but manageable gap compared to the national median of $102,730. The salary range for RNs in this area spans from $61,884 at the 10th percentile to $120,697 at the 90th percentile, highlighting the potential for higher earnings depending on specialty certifications and experience, particularly in high-demand areas like the ICU or emergency departments. These figures are derived from 2025 BLS data, adjusted for local cost variations in the Mount Pleasant market. This region's emphasis on specialty certification, such as CCRN or CEN, can lead to additional compensation, effectively enhancing the base salary for dedicated professionals.
About the Mount Pleasant Market
Salary estimated from South Carolina average ($76,000) adjusted for local cost of living.
Salary Breakdown
| Percentile | Annual | Hourly |
|---|---|---|
| Entry Level (P10) | $61,884 | $29.75 |
| Lower Range (P25) | $69,521 | $33.43 |
| Median (P50)(typical) | $87,258 | $41.96 |
| Upper Range (P75) | $99,721 | $47.95 |
| Top Earners (P90) | $120,697 | $58.03 |
Median Salary Position
15.06% below the national average
2026 Salary Percentile Distribution in Mount Pleasant
In Mount Pleasant, SC, the registered nurse salary spread from the 10th to 90th percentile is $58,813 (2026 est.). At $87,258, the local median is 15.06% below the national median of $102,730.
Salary Calculator
At 40 hours/week in Mount Pleasant: You'd be in the lower-middle range
How Mount Pleasant Registered Nurse Pay Compares
Mount Pleasant median: $87,258/year (2026)
| Compared To | Median Salary | Mount Pleasant Pays |
|---|---|---|
| South Carolina Average | $85,968 | +1.50% more |
| National Average | $102,730 | -15.06% less |
Registered Nurses in Mount Pleasant, SC earn a median of $87,258 per year (2026 est.), which is 15.06% lower than the national median of $102,730 and 1.50% above the South Carolina state average of $85,968.
Cost-of-Living Adjusted Salary
Mount Pleasant has a cost of living 8.50% below the national average, meaning your salary goes further here.
Adjusted salary = nominal × (100 / CoL index). CoL index: 100 = national average.
Mount Pleasant, SC has a cost-of-living index of 91.5 (below the national average of 100). A registered nurse earning $87,258 nominally has purchasing power equivalent to $95,364 in an average-cost city — an effective 9.29% boost.
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2019 BLS Actual
$62,260
2025 BLS Actual
$82,858
2026 Current Est.
$87,258
2019–2027 Growth
+47.6%
Salary Trajectory for Registered Nurses in Mount Pleasant (2019–2027)
2019–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 5.31% projection.
| Year | Annual Salary | Status |
|---|---|---|
| 2019 | $62,260 | Actual |
| 2020 | $63,985 | Actual |
| 2021 | $65,913 | Actual |
| 2022 | $68,987 | Actual |
| 2023 | $73,107 | Actual |
| 2024 | $70,560 | Actual |
| 2025 | $82,858 | Actual |
| 2026(current) | $87,258 | Estimated |
| 2027 | $91,891 | Projected |
Based on 7 years of BLS OEWS data for the Mount Pleasant metropolitan area, the median registered nurse salary grew 33.1% from $62,260 (2019) to $82,858 (2025). At a 5.31% compound annual growth rate, salaries are projected to reach $91,891 by 2027 — a total increase of $29,631 (47.59%) from 2019.
Note: Historical values (2019–2025) are actual BLS OEWS figures for the Mount Pleasant metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 5.31% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Salary by Experience Level
| Experience | Estimated Salary Range |
|---|---|
| 0-2 years (New Graduate) | $61,884 – $69,521 |
| 3-5 years (Mid Career) | $69,521 – $87,258 |
| 5+ years (Experienced) | $87,258 – $99,721 |
| 10+ years (Top Earner) | $99,721 – $120,697 |
RN salary ranges estimated from BLS percentile data. Individual registered nurse compensation varies by employer, certifications, and specialization.
Registered Nurse Job Market in Mount Pleasant
The local job market in Mount Pleasant currently employs 19 registered nurses, reflecting the area's healthcare demand. With a cost-of-living index of 91.5, RNs can enjoy better purchasing power compared to many other regions of the country, allowing for a comfortable lifestyle. Hospitals and health systems, especially those with magnet status, often offer the highest salaries, particularly for shifts in high-acuity areas where nurses can earn substantial shift differentials. Highly specialized roles in surgical centers or travel nursing arrangements also appeal to those looking to maximize earnings. For registered nurses considering their earning potential in Mount Pleasant, pursuing ongoing education and specialty certifications while strategically choosing shift patterns can significantly influence overall compensation.
More salary data for Mount Pleasant, SC:
Frequently Asked Questions
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Written by Jordan Lee, RN, BSN
Career Analyst
Jordan Lee has 10 years of experience as a registered nurse. Their specialty is pediatric nursing in a community hospital. They analyze nursing workforce trends and salary data.
Methodology & Data Source
Salary figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. The BLS reported a median annual salary of $82,858 for registered nursesin the Mount Pleasant metropolitan area. A 5.31% compound annual growth rate (CAGR), calculated from 6-year national BLS wage trends, was applied to project current 2026 compensation. Percentile ranges (P10–P90) represent the full salary distribution across experience levels and practice settings in this market.
Data Sources & Methodology
Salary data for Mount Pleasant is estimated from official BLS state-level occupational wage data (2025), adjusted for regional cost-of-living differences using BEA RPP (Regional Price Parities).
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 5.31%, derived from historical BLS wage trends for registered nurses (SOC 29-1141).
Compiled and verified by Jordan Lee, RN, BSN, a licensed registered nurse with 10+ years of clinical experience. · View source data at BLS.gov